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Filler material injection is generally applied for filling deep lines and pits formed with ageing on face and thickening lips and sometimes correcting contours. The materials used under the skin for this purpose are called "fillers". 

Filler materials are generally comprised of the products obtained in the laboratories as a result of synthetically chemical reactions. Equivalents of some materials available in a body or chemical synthetic materials to be replaced for them can be made use of. Some of synthetic products have risk of causing allergy with low rates. 

"Hyaluronic acid" constituting main ingredient of the most frequently used products are naturally available inside skin, bone, cartilage tissue and our several tissues in our body. 

Tissue cocktails formed from fat and dermis removed with liposuction of a person as well as these products and healing tissues under old scars are frequently used for this purpose. 

Persistence of these filler materials is variable and those with the longest persistence are the products prepared from the person's own tissues.

Fat Injection
Fat cells obtained by means of a vacuum injector from abdomen, legs or hips, are transferred to another area of a body with the help of a special application tool after separating from unnecessary wastes with a set of filtration procedure. Fat cell can live to the extent where they can be fed in their transported location and can cause a permanent fullness. All fat cells generally transferred cannot survive. However, they can survive alive in the rate up to 70% with a meticulous fat injection. Generally performed under local anesthesia, this operation ensures safer, natural and permanent result even if it is partially when compared with other filler materials. Another fat injection may be considered on the same area if necessary.

Hyaluronic acid (Restylane) 
Hyaluronic acid is one of the building stones of subcutaneous skin. It is naturally available all humans and animals. Hyaluronic acids with animal origin have been used as filler materials for long years. However, proteins with animal origin may lead to unwanted allergic tissue reactions. In recent years, they have been started to be produced synthetically in a laboratories. Synthetic hyaluronic acid (Restylane) can be used as filling material texture much more safely. Hyaluronic acid injection is a procedure not require operating conditions and generally without administering any anesthesia process.  Material is not permanent; it melts completely within 6-12 months. Re-administration is always possible.